MAP4K4 anticorps (pSer629)
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- Antigène Voir toutes MAP4K4 Anticorps
- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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Épitope
- pSer629
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAP4K4 est non-conjugé
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Application
- Dot Blot (DB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This Phospho-MAP4K4-pS629 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S629 of human MAP4K4.
- Clone
- RB12877
- Isotype
- IgG
- Top Product
- Discover our top product MAP4K4 Anticorps primaire
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- Indications d'application
- DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
- Autre désignation
- MAP4K4 (MAP4K4 Produits)
- Synonymes
- anticorps FLH21957, anticorps HGK, anticorps MEKKK4, anticorps NIK, anticorps 9430080K19Rik, anticorps AU043147, anticorps AU045934, anticorps AW046177, anticorps Nik, anticorps mitogen-activated protein kinase kinase kinase kinase 4, anticorps MAP4K4, anticorps Map4k4
- Sujet
- M4K4, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.
- Poids moléculaire
- 142101
- ID gène
- 9448
- NCBI Accession
- NP_001229488, NP_004825, NP_663720
- UniProt
- O95819
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