TNK2 anticorps (pTyr518)
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- Antigène Voir toutes TNK2 Anticorps
- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
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Épitope
- pTyr518
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TNK2 est non-conjugé
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Application
- Dot Blot (DB)
- Homologie
- B
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This ACK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1.
- Clone
- RB15592
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TNK2 Anticorps primaire
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- Indications d'application
- DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
- Autre désignation
- ACK1 (TNK2 Produits)
- Synonymes
- anticorps ACK, anticorps ACK-1, anticorps ACK1, anticorps p21cdc42Hs, anticorps AW552477, anticorps Ack, anticorps Cdgip, anticorps Pyk1, anticorps ack1, anticorps ackb, anticorps tnk2, anticorps tnk2b, anticorps wu:fj16g04, anticorps zgc:154019, anticorps tyrosine kinase non receptor 2, anticorps tyrosine kinase, non-receptor, 2, anticorps tyrosine kinase, non-receptor, 1, anticorps TNK2, anticorps Tnk2, anticorps tnk1
- Sujet
- ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.
- Poids moléculaire
- 114569
- ID gène
- 10188
- NCBI Accession
- NP_001010938, NP_005772
- UniProt
- Q07912
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