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ANTXR1 anticorps (pTyr425)

ANTXR1 Reactivité: Humain DB Hôte: Lapin Polyclonal RB16635 unconjugated
N° du produit ABIN389986
  • Antigène Voir toutes ANTXR1 Anticorps
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Épitope
    • 15
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr425
    Reactivité
    • 74
    • 35
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 68
    • 3
    • 3
    Lapin
    Clonalité
    • 71
    • 3
    Polyclonal
    Conjugué
    • 28
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ANTXR1 est non-conjugé
    Application
    • 43
    • 29
    • 13
    • 13
    • 13
    • 12
    • 7
    • 5
    • 3
    • 3
    • 3
    Dot Blot (DB)
    Homologie
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y425 of human ANTXR1.
    Clone
    RB16635
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ANTXR1 Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Autre désignation
    ANTXR1 (ANTXR1 Produits)
    Synonymes
    anticorps ANTXR1, anticorps ATR, anticorps TEM8, anticorps 2310008J16Rik, anticorps 2810405N18Rik, anticorps Antrx1, anticorps Tem8, anticorps anthrax toxin receptor 1, anticorps ANTXR1, anticorps Antxr1
    Sujet
    ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
    Poids moléculaire
    62789
    ID gène
    84168
    NCBI Accession
    NP_060623, NP_115584, NP_444262
    UniProt
    Q9H6X2
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