PDX1 anticorps (pThr11)
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- Antigène Voir toutes PDX1 Anticorps
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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Épitope
- pThr11
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PDX1 est non-conjugé
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Application
- Dot Blot (DB)
- Homologie
- M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This IPF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T11 of human IPF.
- Clone
- RB16667
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PDX1 Anticorps primaire
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- Indications d'application
- DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- Autre désignation
- IPF (PDX1 Produits)
- Synonymes
- anticorps GSF, anticorps IDX-1, anticorps IPF1, anticorps IUF1, anticorps MODY4, anticorps PDX-1, anticorps STF-1, anticorps ipf1, anticorps PDX1, anticorps IPF-1, anticorps Ipf1, anticorps Mody4, anticorps pdx-1, anticorps Idx1, anticorps Stf1, anticorps zgc:100874, anticorps XlHbox-8, anticorps xlhbox8, anticorps pancreatic and duodenal homeobox 1, anticorps pancreatic and duodenal homeobox 1 S homeolog, anticorps PDX1, anticorps pdx1, anticorps Pdx1, anticorps pdx1.S
- Sujet
- PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in its gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
- Poids moléculaire
- 30771
- ID gène
- 3651
- NCBI Accession
- NP_000200
- UniProt
- P52945
- Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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