Nanog anticorps (pSer71)
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- Antigène Voir toutes Nanog (NANOG) Anticorps
- Nanog (NANOG) (Nanog Homeobox (NANOG))
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Épitope
- pSer71
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Nanog est non-conjugé
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Application
- Immunofluorescence (IF), Dot Blot (DB)
- Homologie
- Pr
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This Nanog Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S71 of human Nanog.
- Clone
- RB18920
- Isotype
- Ig Fraction
- Top Product
- Discover our top product NANOG Anticorps primaire
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- Indications d'application
- IF: 1:10~50. DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Autre désignation
- Nanog (NANOG Produits)
- Synonymes
- anticorps 2410002E02Rik, anticorps ENK, anticorps ecat4, anticorps NANOG, anticorps hacp, anticorps wu:fd19e04, anticorps wu:fd20a07, anticorps zgc:193933, anticorps Nanog homeobox, anticorps nanog homeobox, anticorps Nanog, anticorps NANOG, anticorps nanog
- Sujet
- NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.
- Poids moléculaire
- 34620
- ID gène
- 79923
- NCBI Accession
- NP_079141
- UniProt
- Q9H9S0
- Pathways
- Stem Cell Maintenance
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