Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This MAGEA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human MAGEA10.
anticorps MAGEA10, anticorps CT1.10, anticorps MAGE10, anticorps RGD1563693, anticorps MAGEA11, anticorps MAGE family member A10, anticorps melanoma-associated antigen 10, anticorps melanoma antigen family A, 10, anticorps putative MAGE domain-containing protein MAGEA13P, anticorps MAGEA10, anticorps LOC509805, anticorps Magea10, anticorps LOC492173
Sujet
MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80 % sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.