Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This MAGEA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-198 amino acids from the Central region of human MAGEA9.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Zhang, Zhai, Wang, Feng, Zhu, Xu, Mao, Huang: "High expression of MAGE-A9 in tumor and stromal cells of non-small cell lung cancer was correlated with patient poor survival." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 1, pp. 541-50, (2015) (PubMed).
Zhan, Zhang, Zhang, Ma, Wu, Gu, Li, Yang: "Prognostic value of MAGE-A9 expression in patients with colorectal cancer." dans: Clinics and research in hepatology and gastroenterology, (2015) (PubMed).
Han, Jiang, Wu, Zhang, Lu: "Expression and prognostic value of MAGE-A9 in laryngeal squamous cell carcinoma." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 10, pp. 6734-42, (2014) (PubMed).
anticorps CT1.9, anticorps MAGE9, anticorps MAGEA9B, anticorps MAGEA9, anticorps MAGE family member A9, anticorps melanoma antigen family A, 9B, anticorps melanoma-associated antigen 9, anticorps MAGEA9, anticorps MAGEA9B, anticorps LOC525400
Sujet
MAGEA9 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80 % sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.