MMP25 anticorps (C-Term)

N° du produit ABIN390146

Détail du produit anti-MMP25 anticorps

Antigène: MMP25 (Matrix Metallopeptidase 25 (MMP25))

Épitope: AA 470-499, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP25 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MMP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP25.

Clone: RB2043

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MMP25

Antigène: MMP25 (Matrix Metallopeptidase 25 (MMP25))

Autre désignation: MMP25 (MMP25 Produits)

Synonymes: anticorps MMP-25, anticorps MMP20, anticorps MMP20A, anticorps MMPL1, anticorps MT-MMP 6, anticorps MT-MMP6, anticorps MT6-MMP, anticorps MT6MMP, anticorps MTMMP6, anticorps F730048C11Rik, anticorps Leukolysin, anticorps matrix metallopeptidase 25, anticorps MMP25, anticorps Mmp25

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP20 but has been renamed matrix metalloproteinase 25 (MMP25).

Poids moléculaire: 62554

ID gène: 64386

NCBI Accession: NP_071913

UniProt: Q9NPA2