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Septin 9 anticorps (C-Term)

SEPT9 Reactivité: Humain WB, IHC (p), FACS Hôte: Lapin Polyclonal RB1931 unconjugated
N° du produit ABIN390155
  • Antigène Voir toutes Septin 9 (SEPT9) Anticorps
    Septin 9 (SEPT9)
    Épitope
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 57-85, C-Term
    Reactivité
    • 27
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 4
    Lapin
    Clonalité
    • 26
    • 1
    Polyclonal
    Conjugué
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Septin 9 est non-conjugé
    Application
    • 15
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This SEPT9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the C-terminal region of human SEPT9.
    Clone
    RB1931
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Amir, Golan, Mabjeesh: "Targeted knockdown of SEPT9_v1 inhibits tumor growth and angiogenesis of human prostate cancer cells concomitant with disruption of hypoxia-inducible factor-1 pathway." dans: Molecular cancer research : MCR, Vol. 8, Issue 5, pp. 643-52, (2010) (PubMed).

    Bennett, Romigh, Eng: "Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis." dans: Cancer research, Vol. 69, Issue 24, pp. 9301-5, (2009) (PubMed).

  • Antigène
    Septin 9 (SEPT9)
    Autre désignation
    SEPT9 (SEPT9 Produits)
    Synonymes
    anticorps SEPT9, anticorps msf, anticorps msf1, anticorps napb, anticorps sint1, anticorps pnutl4, anticorps septd1, anticorps af17q25, anticorps septin-9, anticorps AF17q25, anticorps MSF, anticorps MSF1, anticorps NAPB, anticorps PNUTL4, anticorps SINT1, anticorps SeptD1, anticorps Msf, anticorps Sint1, anticorps Eseptin, anticorps Slpa, anticorps cb999, anticorps fb02h06, anticorps sept9, anticorps wu:fb02h06, anticorps septin 9, anticorps septin-9, anticorps septin 9 S homeolog, anticorps septin 9a, anticorps SEPT9, anticorps sept9, anticorps LOC100605286, anticorps sept9.S, anticorps Sept9, anticorps sept9a
    Sujet
    The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.
    Poids moléculaire
    65401
    ID gène
    7975
    NCBI Accession
    NP_001106963, NP_001106964, NP_001106965, NP_001106966, NP_001106967, NP_001106968, NP_006631
    UniProt
    Q9UHD8
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