This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This DSCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DSCR3.
anticorps zgc:92243, anticorps DSCR3, anticorps DKFZp469M1432, anticorps MGC116512, anticorps DCRA, anticorps DSCRA, anticorps AW538125, anticorps Dcra, anticorps DSCR3 arrestin fold containing, anticorps Down syndrome critical region 3, anticorps down syndrome critical region protein 3, anticorps DSCR3 arrestin fold containing L homeolog, anticorps Dscr3, anticorps DSCR3, anticorps dscr3, anticorps CpipJ_CPIJ008672, anticorps PITG_10989, anticorps dscr3.L
Sujet
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.