Kallikrein 5 anticorps (AA 144-174)

N° du produit ABIN390305

Détail du produit anti-Kallikrein 5 anticorps

Antigène: Kallikrein 5 (KLK5)

Épitope: AA 144-174

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 5 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.

Clone: RB6112

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Kallikrein 5 (ABIN390305)

Jennemann, Rabionet, Gorgas, Epstein, Dalpke, Rothermel, Bayerle, van der Hoeven, Imgrund, Kirsch, Nickel, Willecke, Riezman, Gröne, Sandhoff: "Loss of ceramide synthase 3 causes lethal skin barrier disruption." dans: Human molecular genetics, Vol. 21, Issue 3, pp. 586-608, (2012) (PubMed).

Détails sur Kallikrein 5

Antigène: Kallikrein 5 (KLK5)

Abstract: KLK5 Produits

Synonymes: anticorps KLK-L2, anticorps KLKL2, anticorps SCTE, anticorps 1110030O19Rik, anticorps KAL, anticorps KALA, anticorps Klk1, anticorps Klk5, anticorps RATKALA, anticorps kallikrein related peptidase 5, anticorps kallikrein related-peptidase 5, anticorps kallikrein 5-like, anticorps KLK5, anticorps Klk5, anticorps Klk5l

Sujet: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.

Poids moléculaire: 32020

ID gène: 25818

NCBI Accession: NP_001070959, NP_001070960, NP_036559

UniProt: Q9Y337

Pathways: Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling