Paxillin anticorps (AA 94-125)

N° du produit ABIN390376

Détail du produit anti-Paxillin anticorps

Antigène: Paxillin (PXN)

Épitope: AA 94-125

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Paxillin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-125 amino acids from human PXN.

Clone: RB15414

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Paxillin

Antigène: Paxillin (PXN)

Autre désignation: PXN (PXN Produits)

Synonymes: anticorps AW108311, anticorps AW123232, anticorps Pax, anticorps CG18061, anticorps CG18576, anticorps CG31794, anticorps CT40481, anticorps CT42454, anticorps DPaxillin, anticorps DPxn, anticorps DPxn37, anticorps Dmel\\CG31794, anticorps Dpax, anticorps DpaxA, anticorps PDLP, anticorps dPax, anticorps pax, anticorps wu:fw71f12, anticorps PXN, anticorps LOC100220858, anticorps paxillin, anticorps Paxillin, anticorps paxillin S homeolog, anticorps paxillin a, anticorps PXN, anticorps Pxn, anticorps Pax, anticorps pxn.S, anticorps pxna, anticorps LOC696336, anticorps pxn

Sujet: PXN is a cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. PXN contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).

Poids moléculaire: 64505

ID gène: 5829

NCBI Accession: NP_001074324, NP_001230685, NP_002850, NP_079433

UniProt: P49023

Pathways: Signalisation MAPK, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling