SUV420H2/KMT5C anticorps (AA 187-214)

N° du produit ABIN390405

Détail du produit anti-SUV420H2/KMT5C anticorps

Antigène: SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

Épitope: AA 187-214

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUV420H2/KMT5C est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This SUV4-20H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 amino acids of human SUV4-20H2.

Clone: RB19392

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-SUV420H2/KMT5C (ABIN390405)

Boonsanay, Zhang, Georgieva, Kostin, Qi, Yuan, Zhou, Braun: "Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation." dans: Cell stem cell, Vol. 18, Issue 2, pp. 229-42, (2016) (PubMed).

Détails sur SUV420H2/KMT5C

Antigène: SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

Autre désignation: SUV4-20H2 (SUV420H2 Produits)

Synonymes: anticorps zgc:162876, anticorps KMT5C, anticorps BC024816, anticorps Suv4-20h2, anticorps lysine methyltransferase 5C, anticorps suppressor of variegation 4-20 homolog 2 (Drosophila), anticorps lysine (K)-specific methyltransferase 5C L homeolog, anticorps KMT5C, anticorps kmt5c, anticorps SUV420H2, anticorps kmt5c.L, anticorps Kmt5c

Sujet: SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).

Poids moléculaire: 52113

ID gène: 84787

NCBI Accession: NP_116090

UniProt: Q86Y97