This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This COL6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human COL6A1.
anticorps CBR, anticorps SDR21C1, anticorps hCBR1, anticorps OPLL, anticorps AI747156, anticorps Col6a-1, anticorps RGD1565398, anticorps COL6A1, anticorps carbonyl reductase 1, anticorps collagen type VI alpha 1 chain, anticorps collagen, type VI, alpha 1, anticorps collagen, type VI, alpha 1 L homeolog, anticorps collagen type VI alpha 3 chain, anticorps collagen alpha-1(VI) chain, anticorps CBR1, anticorps COL6A1, anticorps Col6a1, anticorps col6a1.L, anticorps COL6A3, anticorps col6a1, anticorps LOC100623720
Sujet
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.