TDG anticorps (C-Term)

N° du produit ABIN390560

Détail du produit anti-TDG anticorps

Antigène: TDG (Thymine-DNA Glycosylase (TDG))

Épitope: AA 281-310, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDG est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This TDG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the C-terminal region of human TDG.

Clone: RB19894

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur TDG

Antigène: TDG (Thymine-DNA Glycosylase (TDG))

Autre désignation: TDG (TDG Produits)

Synonymes: anticorps 5-MCDG, anticorps wu:fb44b11, anticorps zgc:110622, anticorps MGC82456, anticorps MGC89441, anticorps E130317C12Rik, anticorps JZA-3, anticorps Jza1, anticorps hTDG, anticorps thymine DNA glycosylase, anticorps thymine DNA glycosylase, tandem duplicate 1, anticorps putative g/t mismatch-specific thymine DNA glycosylase, anticorps G/T mismatch-specific thymine DNA glycosylase, anticorps thymine DNA glycosylase S homeolog, anticorps thymine-DNA glycosylase, anticorps TDG, anticorps tdg.1, anticorps Smp_149220, anticorps Tsp_05734, anticorps tdg.S, anticorps tdg, anticorps Tdg

Sujet: The protein TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.

Poids moléculaire: 46053

ID gène: 6996

NCBI Accession: NP_003202

UniProt: Q13569

Pathways: Réparation de l'ADN, Chromatin Binding