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MTBP anticorps (C-Term)

Name: MTBP anticorps (C-Term)
SKU: ABIN390601
Price: 445.5 EUR
Availability: InStock

MTBP Reactivité: Humain WB, IHC (p), FACS Hôte: Lapin Polyclonal RB20020 unconjugated

Western blot analysis of MTBP antibody (C-term) (ABIN390601 and ABIN2840917) in K562 cell line lysates (35 μg/lane). (MTBP anticorps (C-Term))

Flow cytometric analysis of K562 cells using MTBP Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. (MTBP anticorps (C-Term))

FACS

Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with MTBP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (MTBP anticorps (C-Term))

IHC (p)

3 images

N° du produit ABIN390601

Fiche de données

Antigène Voir toutes MTBP Anticorps

MTBP (MDM2 Binding Protein (MTBP))
Épitope
15

5

5

3

2

2

1

1

1

1

1
AA 853-881, C-Term
Reactivité
43

18

2

2

2

2

2

2

1

1

1

1

1
Humain
Hôte
41

2
Lapin
Anticorps secondaires appropriés
Clonalité
41

2
Polyclonal
Conjugué
19

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MTBP est non-conjugé
Application
32

14

13

13

6

4

4

3

2

2

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

M

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This MTBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 853-881 amino acids from the C-terminal region of human MTBP.

Clone

RB20020

Isotype

Ig Fraction
anti-MDM2 Binding Protein (MTBP) antibody
MTBP Reactivité: Humain WB, IHC, FACS Hôte: Lapin Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody
MTBP Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 667-812) antibody
MTBP Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal PHL-1 unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 23-350) antibody
MTBP Reactivité: Humain WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (Middle Region 2) antibody
MTBP Reactivité: Humain WB, ELISA, ICC Hôte: Lapin Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 122-139) antibody
MTBP Reactivité: Humain WB, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 122-139), (Middle Region) antibody
MTBP Reactivité: Humain WB, EIA, IF Hôte: Lapin Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (HRP)
MTBP Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (FITC)
MTBP Reactivité: Humain Hôte: Lapin Polyclonal FITC

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (Biotin)
MTBP Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin

Indications d'application

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Antigène

MTBP (MDM2 Binding Protein (MTBP))

Autre désignation

MTBP (MTBP Produits)

Synonymes

anticorps MDM2BP, anticorps AI429604, anticorps MDM2 binding protein, anticorps Mdm2, transformed 3T3 cell double minute p53 binding protein, anticorps MTBP, anticorps Mtbp

Sujet

MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.

Poids moléculaire

102193

ID gène

27085

NCBI Accession

NP_071328

UniProt

Q96DY7