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Glucagon anticorps (C-Term)

Name: Glucagon anticorps (C-Term)
SKU: ABIN390769
Price: 445.5 EUR
Availability: InStock

GCG Reactivité: Humain WB, IF, IHC (p), FACS Hôte: Lapin Polyclonal RB19525 unconjugated

Immunohistochemical analysis of paraffin-embedded Human pancreas section using Pink1 C. (Glucagon anticorps (C-Term))

IHC

Western blot analysis of Glucagon Antibody (C-term) (ABIN390769 and ABIN2841027) in Jurkat cell line lysates (35 μg/lane). (Glucagon anticorps (C-Term))

Confocal immunofluorescent analysis of Glucagon Antibody (C-term) (ABIN390769 and ABIN2841027) with pancreas tissue followed by Alexa Fluor? (Glucagon anticorps (C-Term))

All lanes : Anti-Glucagon Antibody (C-term) at 1:1000 dilution Lane 1: NC-1 whole cell lysate Lane 2: Humanbrain lysate Lane 3: Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. (Glucagon anticorps (C-Term))

Overlay histogram showing Jurkat cells stained with (ABIN390769 and ABIN2841027)(green line). (Glucagon anticorps (C-Term))

FACS

Immunohistochemical analysis of paraffin-embedded human liver tissue using (ABIN390769 and ABIN2841027) performed on the Leica® BOND RXm. (Glucagon anticorps (C-Term))

IHC (p)

6 images

N° du produit ABIN390769

Fiche de données

Antigène Voir toutes Glucagon (GCG) Anticorps

Glucagon (GCG)
Épitope
17

16

10

7

6

6

5

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 119-148, C-Term
Reactivité
134

53

49

16

7

6

4

3

3

3

3

2

2

1

1

1
Humain
Hôte
89

34

14

4

1
Lapin
Anticorps secondaires appropriés
Clonalité
96

45
Polyclonal
Conjugué
80

11

6

5

4

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp Glucagon est non-conjugé
Application
53

52

29

16

15

13

13

11

10

10

9

8

4

3

2

2

2

2

2

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This Glucagon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human Glucagon.

Clone

RB19525

Isotype

Ig Fraction

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GCG Reactivité: Humain ELISA Hôte: Souris Monoclonal 2F9 unconjugated

Indications d'application

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25. IHC: 1:125

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Antigène

Glucagon (GCG)

Autre désignation

Glucagon (GCG Produits)

Synonymes

anticorps GLP1, anticorps GLP2, anticorps GRPP, anticorps GLP-1, anticorps Glu, anticorps PPG, anticorps GCG, anticorps gcg-A, anticorps gcg1, anticorps glucagon, anticorps glucagon L homeolog, anticorps GCG, anticorps Gcg, anticorps gcg.L

Sujet

Glucagon is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Poids moléculaire

20909

ID gène

2641

NCBI Accession

NP_002045

UniProt

P01275

Pathways

Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling