Aurora Kinase C anticorps (AA 115-145)

N° du produit ABIN390979

Détail du produit anti-Aurora Kinase C anticorps

Antigène: Aurora Kinase C (AURKC)

Épitope: AA 115-145

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase C est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-145 amino acids from the Central region of human Aurora-C.

Clone: RB6822

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Aurora Kinase C (ABIN390979)

Burum-Auensen, Skotheim, Schjølberg, Røislien, Lothe, Clausen: "Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors." dans: Journal of carcinogenesis, Vol. 9, pp. 1, (2010) (PubMed).

Détails sur Aurora Kinase C

Antigène: Aurora Kinase C (AURKC)

Autre désignation: Aurora-C (AURKC Produits)

Sujet: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Poids moléculaire: 35591

ID gène: 6795

NCBI Accession: NP_001015878, NP_001015879, NP_003151

UniProt: Q9UQB9

Pathways: Cycle Cellulaire, Maintenance of Protein Location