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PRKD3 anticorps (AA 352-384)

PRKD3 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB1047 unconjugated
N° du produit ABIN391014
  • Antigène Voir toutes PRKD3 Anticorps
    PRKD3 (Protein Kinase D3 (PRKD3))
    Épitope
    • 15
    • 15
    • 10
    • 9
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 352-384
    Reactivité
    • 54
    • 33
    • 20
    • 15
    • 1
    • 1
    Humain
    Hôte
    • 86
    • 3
    Lapin
    Clonalité
    • 85
    • 4
    Polyclonal
    Conjugué
    • 30
    • 8
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PRKD3 est non-conjugé
    Application
    • 77
    • 42
    • 39
    • 26
    • 26
    • 21
    • 14
    • 12
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This PKC-nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-384 amino acids from human PKC-nu.
    Clone
    RB1047
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Chen, Deng, Singh, Wang: "Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2." dans: Cancer research, Vol. 68, Issue 10, pp. 3844-53, (2008) (PubMed).

  • Antigène
    PRKD3 (Protein Kinase D3 (PRKD3))
    Autre désignation
    PKC nu (PRKD3 Produits)
    Synonymes
    anticorps EPK2, anticorps PKC-NU, anticorps PKD3, anticorps PRKCN, anticorps nPKC-NU, anticorps PRKD3, anticorps 4930557O20Rik, anticorps 5730497N19Rik, anticorps Pkcnu, anticorps Prkcn, anticorps protein kinase D3, anticorps PRKD3, anticorps prkd3, anticorps Prkd3
    Sujet
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
    Poids moléculaire
    100471
    ID gène
    23683
    NCBI Accession
    NP_005804
    UniProt
    O94806
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