PRKD3 anticorps (AA 352-384)

N° du produit ABIN391014

Détail du produit anti-PRKD3 anticorps

Antigène: PRKD3 (Protein Kinase D3 (PRKD3))

Épitope: AA 352-384

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKD3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PKC-nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-384 amino acids from human PKC-nu.

Clone: RB1047

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PRKD3 (ABIN391014)

Chen, Deng, Singh, Wang: "Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2." dans: Cancer research, Vol. 68, Issue 10, pp. 3844-53, (2008) (PubMed).

Détails sur PRKD3

Antigène: PRKD3 (Protein Kinase D3 (PRKD3))

Autre désignation: PKC nu (PRKD3 Produits)

Synonymes: anticorps EPK2, anticorps PKC-NU, anticorps PKD3, anticorps PRKCN, anticorps nPKC-NU, anticorps PRKD3, anticorps 4930557O20Rik, anticorps 5730497N19Rik, anticorps Pkcnu, anticorps Prkcn, anticorps protein kinase D3, anticorps PRKD3, anticorps prkd3, anticorps Prkd3

Sujet: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Poids moléculaire: 100471

ID gène: 23683

NCBI Accession: NP_005804

UniProt: O94806