MOBKL1A anticorps (C-Term)

N° du produit ABIN391030

Détail du produit anti-MOBKL1A anticorps

Antigène: MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

Épitope: AA 177-206, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MOBKL1A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MOB4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the C-terminal region of human MOB4A.

Clone: RB12538

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MOBKL1A (ABIN391030)

Nishio, Hamada, Kawahara, Sasaki, Noguchi, Chiba, Mizuno, Suzuki, Dong, Tokuda, Morikawa, Hikasa, Eggenschwiler, Yabuta, Nojima, Nakagawa, Hata, Nishina, Mimori, Mori, Sasaki, Mak, Nakano, Itami et al.: "Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. ..." dans: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4505-18, (2012) (PubMed).

Wilmeth, Shrestha, Montaño, Rashe, Shuster: "Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis." dans: Molecular biology of the cell, Vol. 21, Issue 3, pp. 380-92, (2010) (PubMed).

Détails sur MOBKL1A

Antigène: MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

Autre désignation: MOB4A (MOB1B Produits)

Synonymes: anticorps MATS2, anticorps MOB4A, anticorps MOBKL1A, anticorps 1110003E08Rik, anticorps AU015450, anticorps B230364F10, anticorps Mobkl1a, anticorps mobkl1a, anticorps mobkl1aa, anticorps wu:fj65h03, anticorps zgc:56156, anticorps zgc:77872, anticorps MOB1B, anticorps mob4a, anticorps mats2, anticorps C2orf6, anticorps MOB1, anticorps MOBK1B, anticorps Mob4B, anticorps cb512, anticorps mobkl1ab, anticorps sb:cb512, anticorps zgc:111840, anticorps MOB kinase activator 1B, anticorps MOB kinase activator 1Ba, anticorps Mps one binder kinase activator-like 1A, anticorps mps one binder kinase activator-like 1A, anticorps MOB kinase activator 1B L homeolog, anticorps MOB kinase activator 1Bb, anticorps MOB1B, anticorps Mob1b, anticorps mob1ba, anticorps mol1a, anticorps LOC100282811, anticorps LOC100285953, anticorps mob1b, anticorps mob1b.L, anticorps mob1bb

Sujet: MOB4A is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Mob4A regulates NDR1 and NDR2 kinase activity, widely expressed nuclear serine-threonine kinases that have been implicated in cell proliferation and/or tumor progression.

Poids moléculaire: 25091

ID gène: 92597

NCBI Accession: NP_001231695, NP_775739

UniProt: Q7L9L4