PKM2 anticorps (N-Term)

N° du produit ABIN391052

Détail du produit anti-PKM2 anticorps

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Épitope: AA 121-151, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKM2 est non-conjugé

Application: Western Blotting (WB)

Homologie: Rb, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-151 amino acids from the N-terminal region of human Pyruvate Kinase (PKM2).

Clone: RB5870

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PKM2 (ABIN391052)

Shin, Yoo, Hong, Chang, Jung, Jeong, Park: "Upregulation of glycolytic enzymes in proteins secreted from human colon cancer cells with 5-fluorouracil resistance." dans: Electrophoresis, Vol. 30, Issue 12, pp. 2182-92, (2009) (PubMed).

Détails sur PKM2

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Autre désignation: Pyruvate Kinase (PKM2) (PKM2 Produits)

Synonymes: anticorps CTHBP, anticorps OIP3, anticorps PK3, anticorps PKM2, anticorps TCB, anticorps THBP1, anticorps AA414905, anticorps AL024370, anticorps AL024424, anticorps Pk-2, anticorps Pk-3, anticorps Pk3, anticorps Pkm2, anticorps PKM12, anticorps PKM, anticorps pyruvate kinase M1/2, anticorps pyruvate kinase, muscle, anticorps PKM, anticorps Pkm

Sujet: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Poids moléculaire: 57937

ID gène: 5315

NCBI Accession: NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271

UniProt: P14618

Pathways: L'effet Warburg