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PKM2 anticorps (C-Term)

Name: PKM2 anticorps (C-Term)
SKU: ABIN391053
Price: 445.5 EUR
Availability: InStock

PKM2 Reactivité: Humain, Souris, Rat, Singe WB, IHC (p), IF Hôte: Lapin Polyclonal RB3697 unconjugated

All lanes : Anti-PKM2 Antibody at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 μg per lane. (PKM2 anticorps (C-Term))

Pyruvate Kinase (PKM2) Antibody (C-term) (ABIN391053 and ABIN2837941) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (PKM2 anticorps (C-Term))

IHC (p)

Western blot analysis of hPKM2- in cell line(lane 1) and mouse brain tissue(lane 2) lysates (35 μg/lane). (PKM2 anticorps (C-Term))

Fluorescent confocal image of MCF7 cells stained with Pyruvate Kinase (PKM2) (C-term) antibody. (PKM2 anticorps (C-Term))

All lanes : Anti-hPKM2- at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: A549 whole cell lysate Lane 3: NIH/3T3 whole cell lysate Lane 4: C2C12 whole cell lysate Lane 5: PC-12 whole cell lysate Lysates/proteins at 20 μg per lane. (PKM2 anticorps (C-Term))

5 images

(1 reference)

N° du produit ABIN391053

Fiche de données

Antigène Voir toutes PKM2 Anticorps

PKM2 (Pyruvate Kinase M2 (PKM2))
Épitope
21

16

16

11

7

7

7

7

7

6

6

6

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 476-505, C-Term
Reactivité
149

104

92

4

3

2

2

2

2

2

1

1

1
Humain, Souris, Rat, Singe
Hôte
127

22

5
Lapin
Anticorps secondaires appropriés
Clonalité
133

21
Polyclonal
Conjugué
57

12

9

9

9

9

9

9

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1
Cet anticorp PKM2 est non-conjugé
Application
85

34

27

27

23

19

14

11

9

7

7

5

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).

Clone

RB3697

Isotype

Ig Fraction

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anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibody
PKM2 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibody
PKM2 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibody
PKM2 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB18405 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibody
PKM2 Reactivité: Humain, Souris, Rat, Primate WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibody
PKM2 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Lapin Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibody
PKM2 Reactivité: Humain, Souris, Rat WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 121-151), (N-Term) antibody
PKM2 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB5870 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145), (N-Term) antibody
PKM2 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB15338 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibody
PKM2 Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated

Indications d'application

IF: 1:200. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~1:100

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid freeze-thaw cycles.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption

6 months
Kienzl, Sarg, Golderer, Obrist, Werner, Werner-Felmayer, Lindner, Maglione, Schneeberger, Margreiter, Brandacher: "Proteomic profiling of acute cardiac allograft rejection." dans: Transplantation, Vol. 88, Issue 4, pp. 553-60, (2009) (PubMed).
Antigène

PKM2 (Pyruvate Kinase M2 (PKM2))

Autre désignation

PKM2 (PKM2 Produits)

Synonymes

anticorps CTHBP, anticorps OIP3, anticorps PK3, anticorps PKM2, anticorps TCB, anticorps THBP1, anticorps AA414905, anticorps AL024370, anticorps AL024424, anticorps Pk-2, anticorps Pk-3, anticorps Pk3, anticorps Pkm2, anticorps PKM12, anticorps PKM, anticorps pyruvate kinase M1/2, anticorps pyruvate kinase, muscle, anticorps PKM, anticorps Pkm

Sujet

There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Poids moléculaire

57937

ID gène

5315

NCBI Accession

NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271

UniProt

P14618

Pathways

L'effet Warburg