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PKM2 anticorps (C-Term)

PKM2 Reactivité: Humain, Souris, Rat, Singe WB, IHC (p), IF Hôte: Lapin Polyclonal RB3697 unconjugated
N° du produit ABIN391053
  • Antigène Voir toutes PKM2 Anticorps
    PKM2 (Pyruvate Kinase M2 (PKM2))
    Épitope
    • 21
    • 16
    • 16
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 476-505, C-Term
    Reactivité
    • 149
    • 104
    • 92
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Singe
    Hôte
    • 127
    • 22
    • 5
    Lapin
    Clonalité
    • 133
    • 21
    Polyclonal
    Conjugué
    • 57
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp PKM2 est non-conjugé
    Application
    • 85
    • 34
    • 27
    • 27
    • 23
    • 19
    • 14
    • 11
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).
    Clone
    RB3697
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PKM2 Anticorps primaire
  • Indications d'application
    IF: 1:200. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze-thaw cycles.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Date de péremption
    6 months
  • Kienzl, Sarg, Golderer, Obrist, Werner, Werner-Felmayer, Lindner, Maglione, Schneeberger, Margreiter, Brandacher: "Proteomic profiling of acute cardiac allograft rejection." dans: Transplantation, Vol. 88, Issue 4, pp. 553-60, (2009) (PubMed).

  • Antigène
    PKM2 (Pyruvate Kinase M2 (PKM2))
    Autre désignation
    PKM2 (PKM2 Produits)
    Synonymes
    anticorps CTHBP, anticorps OIP3, anticorps PK3, anticorps PKM2, anticorps TCB, anticorps THBP1, anticorps AA414905, anticorps AL024370, anticorps AL024424, anticorps Pk-2, anticorps Pk-3, anticorps Pk3, anticorps Pkm2, anticorps PKM12, anticorps PKM, anticorps pyruvate kinase M1/2, anticorps pyruvate kinase, muscle, anticorps PKM, anticorps Pkm
    Sujet
    There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
    Poids moléculaire
    57937
    ID gène
    5315
    NCBI Accession
    NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271
    UniProt
    P14618
    Pathways
    L'effet Warburg
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