CKM anticorps (C-Term)

N° du produit ABIN391096

Détail du produit anti-CKM anticorps

Antigène: CKM (Creatine Kinase, Muscle (CKM))

Épitope: AA 283-313, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: B, Pig, Rb

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CKM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the C-terminal region of human CKM.

Clone: RB5382

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CKM (ABIN391096)

Yang, Fann, Chang, Tai, Jiang, Kao: "Regulation of sodium-calcium exchanger activity by creatine kinase under energy-compromised conditions." dans: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 28275-85, (2010) (PubMed).

Détails sur CKM

Antigène: CKM (Creatine Kinase, Muscle (CKM))

Autre désignation: CKM (CKM Produits)

Synonymes: anticorps CKMM, anticorps M-CK, anticorps Ckmm, anticorps MCK, anticorps ckmm, anticorps m-ck, anticorps CKM, anticorps CK-M, anticorps cb51, anticorps ckm, anticorps mck, anticorps wu:fa28d05, anticorps ckm3, anticorps wu:fb55e09, anticorps zgc:64204, anticorps zgc:92070, anticorps creatine kinase, M-type, anticorps creatine kinase, muscle, anticorps creatine kinase, M-type L homeolog, anticorps creatine kinase, muscle a, anticorps creatine kinase, muscle b, anticorps CKM, anticorps Ckm, anticorps ckm.L, anticorps ckm, anticorps ckma, anticorps ckmb

Sujet: Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. The CKM isoform, predominant in skeletal muscle and heart tissue, is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

Poids moléculaire: 43101

ID gène: 1158

NCBI Accession: NP_001815

UniProt: P06732