PDXK anticorps (N-Term)

N° du produit ABIN391110

Détail du produit anti-PDXK anticorps

Antigène: PDXK (Pyridoxal Kinase (PDXK))

Épitope: AA 1-30, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDXK est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PDXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDXK.

Clone: RB5460

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur PDXK

Antigène: PDXK (Pyridoxal Kinase (PDXK))

Autre désignation: PDXK (PDXK Produits)

Synonymes: anticorps C21orf124, anticorps C21orf97, anticorps PKH, anticorps PNK, anticorps 2310036D04Rik, anticorps AA119688, anticorps C77999, anticorps Pdxk, anticorps PSPTO5521, anticorps DDBDRAFT_0190079, anticorps DDBDRAFT_0191114, anticorps DDB_0190079, anticorps DDB_0191114, anticorps ATSOS4, anticorps K18L3.1, anticorps K18L3_1, anticorps SALT OVERLY SENSITIVE 4, anticorps pdxk, anticorps si:dkey-263m10.2, anticorps si:dz69g10.1, anticorps cb1056, anticorps pdxkl, anticorps si:dkey-281i8.2, anticorps wu:fa55a03, anticorps wu:fb10c12, anticorps zgc:101900, anticorps pyridoxal kinase, anticorps pyridoxal (pyridoxine, vitamin B6) kinase, anticorps Pyridoxal kinase, anticorps pfkB-like carbohydrate kinase family protein, anticorps pyridoxal (pyridoxine, vitamin B6) kinase b, anticorps pyridoxal (pyridoxine, vitamin B6) kinase a, anticorps PDXK, anticorps Pdxk, anticorps pdxY, anticorps pdxK, anticorps Bphyt_1541, anticorps pykA, anticorps Kfla_4736, anticorps Kvar_1290, anticorps Mrub_2507, anticorps BC1002_1103, anticorps Fbal_1661, anticorps Lbys_0710, anticorps Intca_0131, anticorps Deima_3190, anticorps Mesop_1158, anticorps LOC100283562, anticorps pdxk, anticorps SOS4, anticorps pdxkb, anticorps pdxka

Sujet: Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.

Poids moléculaire: 35102

ID gène: 8566

NCBI Accession: NP_003672

UniProt: O00764