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ADK anticorps (N-Term)

ADK Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB05253-05254 unconjugated
N° du produit ABIN391131
  • Antigène Voir toutes ADK Anticorps
    ADK (Adenosine Kinase (ADK))
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-65, N-Term
    Reactivité
    • 50
    • 26
    • 11
    Humain, Souris
    Hôte
    • 44
    • 8
    Lapin
    Clonalité
    • 45
    • 6
    Polyclonal
    Conjugué
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADK est non-conjugé
    Application
    • 40
    • 28
    • 14
    • 10
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-65 amino acids from the N-terminal region of human ADK.
    Clone
    RB05253-05254
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ADK Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    ADK (Adenosine Kinase (ADK))
    Autre désignation
    ADK (ADK Produits)
    Synonymes
    anticorps AK, anticorps ADK, anticorps DDBDRAFT_0186795, anticorps DDBDRAFT_0230174, anticorps DDB_0186795, anticorps DDB_0230174, anticorps ATPADK1, anticorps F3G5.4, anticorps F3G5_4, anticorps adenosine kinase, anticorps adk, anticorps 2310026J05Rik, anticorps 5033405D03Rik, anticorps AI255373, anticorps AI987814, anticorps Ak, anticorps adenosine kinase, anticorps ATP:adenosine 5'-phosphotransferase, anticorps Adenosine kinase, anticorps adenosine kinase S homeolog, anticorps ADK, anticorps adk, anticorps Adk, anticorps CNN02130, anticorps LOC5572668, anticorps CMU_026370, anticorps adk.S
    Sujet
    Adenosine kinase (ATP:adenosine 5-prime-phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well-characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin. Animal studies have demonstrated that a deficiency of adenosine metabolism a powerful contributor to the development of neonatal hepatic steatosis, providing a model for the rapid development of postnatally lethal fatty liver.
    Poids moléculaire
    40545
    ID gène
    132
    NCBI Accession
    NP_001114, NP_001189378, NP_001189379, NP_006712
    UniProt
    P55263
    Pathways
    Ribonucleoside Biosynthetic Process
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