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PNCK anticorps (C-Term)

PNCK Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB1253-1254 unconjugated
N° du produit ABIN391139
  • Antigène Voir toutes PNCK Anticorps
    PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
    Épitope
    • 15
    • 14
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 314-343, C-Term
    Reactivité
    • 53
    • 13
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 51
    • 2
    Lapin
    Clonalité
    • 53
    Polyclonal
    Conjugué
    • 14
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PNCK est non-conjugé
    Application
    • 27
    • 22
    • 13
    • 13
    • 9
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This PNCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human PNCK.
    Clone
    RB1253-1254
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Deb, Zuo, Wang, Barndt, Cheema, Sengupta, Coticchia, Johnson: "Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex." dans: American journal of physiology. Cell physiology, Vol. 300, Issue 5, pp. C1139-54, (2011) (PubMed).

    Deb, Coticchia, Barndt, Zuo, Dickson, Johnson: "Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation." dans: American journal of physiology. Cell physiology, Vol. 295, Issue 2, pp. C365-77, (2008) (PubMed).

  • Antigène
    PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
    Autre désignation
    PNCK (PNCK Produits)
    Synonymes
    anticorps BSTK3, anticorps CaMK1b, anticorps Bstk3, anticorps CaMKIbeta2, anticorps CaMKlb2, anticorps Camk1b, anticorps Punc, anticorps caMKlb1, anticorps pregnancy up-regulated nonubiquitous CaM kinase, anticorps pregnancy upregulated non-ubiquitously expressed CaM kinase, anticorps PNCK, anticorps Pnck
    Sujet
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
    Poids moléculaire
    38500
    ID gène
    139728
    NCBI Accession
    NP_001034671, NP_001129212
    UniProt
    Q6P2M8
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