Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human CAMKK2.
anticorps CAMKK, anticorps CAMKKB, anticorps 6330570N16Rik, anticorps AW061083, anticorps mKIAA0787, anticorps camk2b, anticorps fj90d04, anticorps wu:fj90d04, anticorps si:dkey-174n20.2, anticorps CAMKK2, anticorps calcium/calmodulin dependent protein kinase kinase 2, anticorps calcium/calmodulin-dependent protein kinase kinase 2, beta, anticorps calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1, anticorps calcium/calmodulin dependent protein kinase II beta, anticorps calcium/calmodulin-dependent protein kinase kinase 2, anticorps CAMKK2, anticorps Camkk2, anticorps camk2b1, anticorps CAMK2B, anticorps camkk2
Sujet
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.