ERN2 anticorps (N-Term)
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- Antigène Voir toutes ERN2 Anticorps
- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
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Épitope
- AA 39-72, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ERN2 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogène
- This ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-72 amino acids from the N-terminal region of human ERN2.
- Clone
- RB8519
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ERN2 Anticorps primaire
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- Indications d'application
- WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
- Autre désignation
- ERN2 (ERN2 Produits)
- Sujet
- ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
- Poids moléculaire
- 102480
- ID gène
- 10595
- NCBI Accession
- NP_150296
- UniProt
- Q76MJ5
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