MARK4 anticorps (C-Term)

N° du produit ABIN391222

Détail du produit anti-MARK4 anticorps

Antigène: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Épitope: AA 611-641, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARK4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MARK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-641 amino acids from the C-terminal region of human MARK4.

Clone: RB5447

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MARK4

Antigène: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Autre désignation: MARK4 (MARK4 Produits)

Synonymes: anticorps MARK4, anticorps MARK4L, anticorps MARK4S, anticorps MARKL1, anticorps MARKL1L, anticorps PAR-1D, anticorps 2410090P21Rik, anticorps C79806, anticorps Markl1, anticorps microtubule affinity regulating kinase 4, anticorps MAP/microtubule affinity regulating kinase 4, anticorps MARK4, anticorps Mark4

Sujet: MARK4 contains an N-terminal serine/threonine kinase domain, a central ubiquitin-associated domain, and a C-terminal KA1-associated kinase domain. RT-PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6-kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony-forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells.

Poids moléculaire: 82520

ID gène: 57787

NCBI Accession: NP_001186796, NP_113605

UniProt: Q96L34