PANK2 anticorps (AA 180-210)
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- Antigène Voir toutes PANK2 Anticorps
- PANK2 (Pantothenate Kinase 2 (PANK2))
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Épitope
- AA 180-210
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PANK2 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogène
- This PANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-210 amino acids from the Central region of human PANK2.
- Clone
- RB5487
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PANK2 Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- PANK2 (Pantothenate Kinase 2 (PANK2))
- Autre désignation
- PANK2 (PANK2 Produits)
- Sujet
- Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine. CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism. In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable. Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS). PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).
- Poids moléculaire
- 62681
- ID gène
- 80025
- NCBI Accession
- NP_079236, NP_705902, NP_705904
- UniProt
- Q9BZ23
- Pathways
- Ribonucleoside Biosynthetic Process
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