CAMKII gamma anticorps (C-Term)

N° du produit ABIN391313

Détail du produit anti-CAMKII gamma anticorps

Antigène: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Épitope: AA 309-338, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMKII gamma est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CAMK2G (CAMK2 gamma) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-338 amino acids from the C-terminal region of human CAMK2G (CAMK2 gamma).

Clone: RB1246

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:500-1000. WB: 1:500. WB: 1:2000. IHC-P: 1:50~100. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CAMKII gamma (ABIN391313)

Jiang, Wu, Lu, Zhang, Yu, Gan, Wu, Xu, Zheng, Zhang, Xu, Ma, Gan, Huang, Yu, Huang, Xu: "Activation of CaMKIIγ potentiates T-cell acute lymphoblastic leukemia leukemogenesis via phosphorylating FOXO3a." dans: Oncotarget, Vol. 8, Issue 43, pp. 75050-75064, (2017) (PubMed).

Détails sur CAMKII gamma

Antigène: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Autre désignation: CAMK2G (CAMK2 gamma) (CAMK2G Produits)

Synonymes: anticorps CAMK, anticorps CAMK-II, anticorps CAMKG, anticorps 5930429P18Rik, anticorps Camkg, anticorps calcium/calmodulin dependent protein kinase II gamma, anticorps calcium/calmodulin-dependent protein kinase II gamma, anticorps CAMK2G, anticorps Camk2g

Sujet: CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.

Poids moléculaire: 62607

ID gène: 818

NCBI Accession: NP_001213, NP_751909, NP_751913

UniProt: Q13555

Pathways: Signalisation WNT, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity