MAP3K12 anticorps (C-Term)

N° du produit ABIN391319

Détail du produit anti-MAP3K12 anticorps

Antigène: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Épitope: AA 828-859, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ZPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from the C-terminal region of human ZPK.

Clone: RB0976

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MAP3K12 (ABIN391319)

Ye, Li, Yang, Xie, Yu, Ma, Zhu, Zhao, Lv: "MicroRNA-130a Targets MAP3K12 to Modulate Diabetic Endothelial Progenitor Cell Function." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 2, pp. 712-26, (2015) (PubMed).

Couture, Blouin: "The DLK gene is a transcriptional target of PPAR?." dans: The Biochemical journal, Vol. 438, Issue 1, pp. 93-101, (2011) (PubMed).

Détails sur MAP3K12

Antigène: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Autre désignation: ZPK (MAP3K12 Produits)

Synonymes: anticorps DLK, anticorps MEKK12, anticorps MUK, anticorps ZPK, anticorps ZPKP1, anticorps PK, anticorps Zpk, anticorps zgc:77370, anticorps MGC151798, anticorps dlk, anticorps map3k12, anticorps map3k12a, anticorps mekk12, anticorps muk, anticorps zpk, anticorps zpkp1, anticorps DKFZp459K2433, anticorps map3k12-a, anticorps map3k12-b, anticorps map3k12b, anticorps mitogen-activated protein kinase kinase kinase 12, anticorps mitogen activated protein kinase kinase kinase 12, anticorps mitogen-activated protein kinase kinase kinase 12 S homeolog, anticorps mitogen-activated protein kinase kinase kinase 12 L homeolog, anticorps MAP3K12, anticorps Map3k12, anticorps map3k12, anticorps map3k12.S, anticorps map3k12.L

Sujet: ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.

Poids moléculaire: 93219

ID gène: 7786

NCBI Accession: NP_001180440, NP_006292

UniProt: Q12852

Pathways: Signalisation MAPK