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LKB1 anticorps (N-Term)

Name: LKB1 anticorps (N-Term)
SKU: ABIN391350
Price: 445.5 EUR
Availability: InStock

STK11 Reactivité: Humain WB, IF, IHC (p), FACS Hôte: Lapin Polyclonal RB3547 unconjugated

Western blot analysis of STK11 (arrow) using rabbit polyclonal STK11 Antibody (ABIN391350 and ABIN2841371). (LKB1 anticorps (N-Term))

STK11 (LKB1) Antibody (N-term I29) (ABIN391350 and ABIN2841371) flow cytometric analysis of NCI- cells (right histogram) compared to a negative control cell (left histogram). (LKB1 anticorps (N-Term))

FACS

Confocal immunofluorescent analysis of STK11 (LKB1) Antibody (N-term I29) (ABIN391350 and ABIN2841371) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (LKB1 anticorps (N-Term))

STK11 Antibody (I29) (ABIN391350 and ABIN2841371) western blot analysis in T47D cell line lysates (35 μg/lane). (LKB1 anticorps (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (LKB1 anticorps (N-Term))

IHC (p)

5 images

(1 reference)

N° du produit ABIN391350

Fiche de données

Antigène Voir toutes LKB1 (STK11) Anticorps

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
Épitope
27

26

24

19

15

15

8

7

7

7

6

5

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 14-44, N-Term
Reactivité
188

126

69

16

15

7

6

6

4

3

3

3

2

1

1
Humain
Hôte
192

10
Lapin
Anticorps secondaires appropriés
Clonalité
195

7
Polyclonal
Conjugué
78

11

9

9

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

4

4

2
Cet anticorp LKB1 est non-conjugé
Application
139

73

65

65

32

26

19

15

7

5

3

2

2

2

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

C, M, Rat, X

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1).

Clone

RB3547

Isotype

Ig Fraction

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anti-serine/threonine Kinase 11 (STK11) (AA 14-44) antibody
STK11 Reactivité: Humain WB, ELISA, IHC, IF, FACS Hôte: Lapin Polyclonal unconjugated

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STK11 Reactivité: Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal RB37144 unconjugated

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STK11 Reactivité: Humain, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 19-48) antibody
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STK11 Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) antibody
STK11 Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 4H12 unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 1-433) antibody
STK11 Reactivité: Humain WB, IF, PLA Hôte: Lapin Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (Internal Region) antibody
STK11 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (pThr189) antibody
STK11 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

Indications d'application

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

Date de péremption

6 months
Sohn, Jang, Campan, Weisenberger, Dickhout, Wang, Cho, Yates, Lucock, Chiang, Austin, Choi, Laird, Kim et al.: "The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer ..." dans: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 1999-2005, (2009) (PubMed).
Antigène

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Autre désignation

STK11 (LKB1) (STK11 Produits)

Synonymes

anticorps pjs, anticorps LKB1, anticorps XEEK1, anticorps Stk11, anticorps PJS, anticorps hLKB1, anticorps AA408040, anticorps Lkb1, anticorps Par-4, anticorps R75140, anticorps mLKB1, anticorps wu:fj61a05, anticorps zgc:110180, anticorps xeek1, anticorps serine/threonine kinase 11, anticorps polarization-related protein LKB1, anticorps serine/threonine kinase 11 L homeolog, anticorps STK11, anticorps stk11, anticorps LOC662493, anticorps Stk11, anticorps stk11.L

Sujet

STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

Poids moléculaire

48636

NCBI Accession

NP_000446

UniProt

Q15831

Pathways

AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg