GOPC anticorps (AA 164-193)

N° du produit ABIN391395

Détail du produit anti-GOPC anticorps

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Épitope: AA 164-193

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GOPC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the Central region of human PIST.

Clone: RB13072

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur GOPC

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Autre désignation: PIST (GOPC Produits)

Synonymes: anticorps DKFZp459H2130, anticorps 2210402P09Rik, anticorps AI844555, anticorps CAL, anticorps FIG, anticorps GOPC1, anticorps PIST, anticorps fe38f01, anticorps wu:fe38f01, anticorps zgc:56254, anticorps zgc:65853, anticorps dJ94G16.2, anticorps cal, anticorps gopc1, anticorps pist, anticorps golgi associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing S homeolog, anticorps GOPC, anticorps Gopc, anticorps gopc, anticorps gopc.S

Sujet: PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.

Poids moléculaire: 50520

ID gène: 57120

NCBI Accession: NP_001017408, NP_065132

UniProt: Q9HD26

Pathways: Maintenance of Protein Location, Asymmetric Protein Localization