MYCN anticorps (C-Term)

N° du produit ABIN391590

Détail du produit anti-MYCN anticorps

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Épitope: AA 322-351, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYCN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MYCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the C-terminal region of human MYCN.

Clone: RB18771

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MYCN (ABIN391590)

Li, Sun, Chen, Squires, Nowroozizadeh, Liang, Huang: "p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma." dans: Molecular cancer research : MCR, Vol. 13, Issue 3, pp. 584-91, (2015) (PubMed).

Détails sur MYCN

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Autre désignation: MYCN (MYCN Produits)

Synonymes: anticorps MODED, anticorps MYCNOT, anticorps N-myc, anticorps NMYC, anticorps ODED, anticorps bHLHe37, anticorps Nmyc, anticorps Nmyc-1, anticorps Nmyc1, anticorps c-nmyc, anticorps Nmuc1, anticorps fb57a02, anticorps nmyc1, anticorps wu:fb57a02, anticorps zgc:85706, anticorps XN-myc, anticorps XNmyc, anticorps mycn, anticorps mycn-a, anticorps mycn-b, anticorps mycna, anticorps xN-myc1, anticorps MYCN proto-oncogene, bHLH transcription factor, anticorps v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, anticorps v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived, anticorps olfactory receptor 8S1, anticorps MYCN proto-oncogene, bHLH transcription factor S homeolog, anticorps MYCN, anticorps Mycn, anticorps LOC515887, anticorps mycn, anticorps mycn.S

Sujet: MYCN is a member of the MYC family and a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of its gene is associated with a variety of tumors, most notably neuroblastomas.

Poids moléculaire: 49561

ID gène: 4613

NCBI Accession: NP_005369

UniProt: P04198