CDK10 anticorps (N-Term)

N° du produit ABIN391741

Détail du produit anti-CDK10 anticorps

Antigène: CDK10 (Cyclin-Dependent Kinase 10 (CDK10))

Épitope: AA 1-32, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CDK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human CDK10.

Clone: RB3172

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CDK10 (ABIN391741)

Hong, Zhang, You, Qiu, Giuliano, Cui, Zhang, Cui: "Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study." dans: BMC cancer, Vol. 15, pp. 548, (2015) (PubMed).

You, Li, Qin, Zhang, Song, Ran, Gao: "Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report." dans: Cellular oncology (Dordrecht), Vol. 38, Issue 6, pp. 485-91, (2015) (PubMed).

Leman, Magheli, Yong, Netto, Hinz, Getzenberg: "Identification of nuclear structural protein alterations associated with seminomas." dans: Journal of cellular biochemistry, Vol. 108, Issue 6, pp. 1274-9, (2009) (PubMed).

Iorns, Turner, Elliott, Syed, Garrone, Gasco, Tutt, Crook, Lord, Ashworth: "Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer." dans: Cancer cell, Vol. 13, Issue 2, pp. 91-104, (2008) (PubMed).

Détails sur CDK10

Antigène: CDK10 (Cyclin-Dependent Kinase 10 (CDK10))

Autre désignation: CDK10 (CDK10 Produits)

Synonymes: anticorps PISSLRE, anticorps BC017131, anticorps zgc:110252, anticorps DDBDRAFT_0216532, anticorps DDBDRAFT_0229427, anticorps DDB_0216532, anticorps DDB_0229427, anticorps cdc2rk, anticorps NV16107, anticorps cyclin dependent kinase 10, anticorps cyclin-dependent kinase 10, anticorps CDK family protein kinase, anticorps hypothetical protein, anticorps cyclin-dependent kinase 10 L homeolog, anticorps CDK10, anticorps Cdk10, anticorps cdk10, anticorps LOC5566134, anticorps cdk10.L

Sujet: CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase.

Poids moléculaire: 41038

ID gène: 8558

NCBI Accession: NP_001092003, NP_001153839, NP_443713, NP_443714

UniProt: Q15131