HIPK3 anticorps (C-Term)

N° du produit ABIN391779

Détail du produit anti-HIPK3 anticorps

Antigène: HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))

Épitope: AA 1127-1156, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIPK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1127-1156 amino acids from the C-terminal region of human HIPK3.

Clone: RB3241

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-HIPK3 (ABIN391779)

Lan, Wu, Shih, Chung: "Death-associated protein 6 (Daxx) mediates cAMP-dependent stimulation of Cyp11a1 (P450scc) transcription." dans: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5910-6, (2012) (PubMed).

Tiefenbach, Moll, Nelson, Hu, Baev, Kislinger, Krause: "A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery." dans: PLoS ONE, Vol. 5, Issue 3, pp. e9797, (2010) (PubMed).

Lan, Li, Lin, Lai, Chung: "Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation." dans: Molecular and cellular biology, Vol. 27, Issue 6, pp. 2027-36, (2007) (PubMed).

Détails sur HIPK3

Antigène: HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))

Autre désignation: HIPK3 (HIPK3 Produits)

Sujet: HIPK3 negatively regulates apoptosis by promoting FADD phosphorylation. This kinase enhances androgen receptor-mediated transcription, and may act as a transcriptional corepressor for NK homeodomain transcription factors.

Poids moléculaire: 133743

ID gène: 10114

NCBI Accession: NP_001041665, NP_001265091, NP_001265092, NP_005725

UniProt: Q9H422