EPH Receptor A7 anticorps (C-Term)

N° du produit ABIN391899

Détail du produit anti-EPH Receptor A7 anticorps

Antigène: EPH Receptor A7 (EPHA7)

Épitope: AA 896-925, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: C

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This EphA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 896-925 amino acids from the C-terminal region of human EphA7.

Clone: RB1641-RB1642

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-EPH Receptor A7 (ABIN391899)

Kim, Ibrahim, Wang, Yuan, Evgrafov, Knowles, Wang, Tao, Zhang: "EphA7 regulates spiral ganglion innervation of cochlear hair cells." dans: Developmental neurobiology, (2015) (PubMed).

Brantley-Sieders, Jiang, Sarma, Badu-Nkansah, Walter, Shyr, Chen: "Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome." dans: PLoS ONE, Vol. 6, Issue 9, pp. e24426, (2011) (PubMed).

Wang, Li, Ma, Bao, Wang, Zhou, Sheng, Sugimura, Jin, Zhou: "Differential expression of EphA7 receptor tyrosine kinase in gastric carcinoma." dans: Human pathology, Vol. 38, Issue 11, pp. 1649-56, (2007) (PubMed).

Détails sur EPH Receptor A7

Antigène: EPH Receptor A7 (EPHA7)

Autre désignation: EphA7 (EPHA7 Produits)

Synonymes: anticorps fc51g03, anticorps wu:fc51g03, anticorps si:dkey-23k6.1, anticorps EHK3, anticorps HEK11, anticorps Cek11, anticorps Ebk, anticorps Ehk3, anticorps Hek11, anticorps Mdk1, anticorps CEPHA7, anticorps EPH receptor A7, anticorps eph receptor A7, anticorps ephrin type-B receptor 1-B, anticorps Eph receptor A7, anticorps EPHA7, anticorps epha7, anticorps LOC100166161, anticorps Epha7

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Poids moléculaire: 112097

ID gène: 2045

NCBI Accession: NP_004431

UniProt: Q15375

Pathways: Signalisation RTK