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EPH Receptor B1 anticorps (C-Term)

EPHB1 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB1648 unconjugated
N° du produit ABIN391917
  • Antigène Voir toutes EPH Receptor B1 (EPHB1) Anticorps
    EPH Receptor B1 (EPHB1)
    Épitope
    • 22
    • 15
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 955-984, C-Term
    Reactivité
    • 57
    • 48
    • 40
    • 1
    Humain, Souris
    Hôte
    • 64
    • 4
    • 4
    Lapin
    Clonalité
    • 70
    • 2
    Polyclonal
    Conjugué
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPH Receptor B1 est non-conjugé
    Application
    • 62
    • 27
    • 27
    • 27
    • 13
    • 11
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This EphB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 955-984 amino acids from the C-terminal region of human EphB1.
    Clone
    RB1648
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Sheng, Wang, Dong, Ma, Zhou, Sugimura, Lu, Zhou: "EphB1 is underexpressed in poorly differentiated colorectal cancers." dans: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 75, Issue 5, pp. 274-80, (2008) (PubMed).

    Wang, Dong, Sheng, Ma, Li, Wang, Lu, Sugimura, Jin, Zhou: "Loss of expression of EphB1 protein in gastric carcinoma associated with invasion and metastasis." dans: Oncology, Vol. 73, Issue 3-4, pp. 238-45, (2008) (PubMed).

  • Antigène
    EPH Receptor B1 (EPHB1)
    Autre désignation
    EphB1 (EPHB1 Produits)
    Synonymes
    anticorps ELK, anticorps EPHT2, anticorps Hek6, anticorps NET, anticorps ephb1-a, anticorps xek, anticorps Xek, anticorps MGC89790, anticorps EPHB1, anticorps CEK6, anticorps EK6, anticorps 9330129L11, anticorps AW488255, anticorps C130099E04Rik, anticorps Cek6, anticorps ENSMUSG00000074119, anticorps Elk, anticorps Elkh, anticorps Net, anticorps Ephb2, anticorps Erk, anticorps elk, anticorps EPH receptor B1, anticorps EPH receptor B1 S homeolog, anticorps ephrin type-B receptor 1, anticorps Eph receptor B1, anticorps EPHB1, anticorps ephb1.S, anticorps ephb1, anticorps LOC100467687, anticorps Ephb1
    Sujet
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
    Poids moléculaire
    109885
    ID gène
    2047
    NCBI Accession
    NP_004432
    UniProt
    P54762
    Pathways
    Signalisation RTK
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