EPH Receptor B2 anticorps

N° du produit ABIN391921

Détail du produit anti-EPH Receptor B2 anticorps

Antigène: EPH Receptor B2 (EPHB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This EphB2 antibody is generated from rabbits immunized with a recombinant human EphB2 protein.

Clone: RB15188

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur EPH Receptor B2

Antigène: EPH Receptor B2 (EPHB2)

Autre désignation: EphB2 (EPHB2 Produits)

Synonymes: anticorps CAPB, anticorps DRT, anticorps EK5, anticorps EPHT3, anticorps ERK, anticorps Hek5, anticorps PCBC, anticorps Tyro5, anticorps ERK2, anticorps ERT1, anticorps MAPK2, anticorps P42MAPK, anticorps PRKM1, anticorps PRKM2, anticorps p38, anticorps p40, anticorps p41, anticorps p41mapk, anticorps RGD1564232, anticorps Cek5, anticorps Drt, anticorps ETECK, anticorps Erk, anticorps Nuk, anticorps Prkm5, anticorps Qek5, anticorps Sek3, anticorps cek5, anticorps ephb2, anticorps xEphB2, anticorps si:ch73-160e9.1, anticorps tpx2, anticorps wu:fb09e10, anticorps wu:fc64a03, anticorps wu:fi18g12, anticorps zgc:112296, anticorps EPH receptor B2, anticorps mitogen-activated protein kinase 1, anticorps Eph receptor B2, anticorps EPH receptor B2 L homeolog, anticorps eph receptor B2a, anticorps eph receptor B2b, anticorps EPHB2, anticorps MAPK1, anticorps Ephb2, anticorps ephb2.L, anticorps ephb2a, anticorps ephb2b

Sujet: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.

Poids moléculaire: 117493

ID gène: 2048

NCBI Accession: NP_004433, NP_059145

UniProt: P29323

Pathways: Signalisation RTK, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins