EPH Receptor B3 anticorps (N-Term)

N° du produit ABIN391922

Détail du produit anti-EPH Receptor B3 anticorps

Antigène: EPH Receptor B3 (EPHB3)

Épitope: AA 29-59, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This EphB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the N-terminal region of human EphB3.

Clone: RB1653

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-EPH Receptor B3 (ABIN391922)

Gao, Zhang, Wang, Wang, Zhang: "EphB3 protein is associated with histological grade and FIGO stage in ovarian serous carcinomas." dans: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 2, pp. 122-127, (2017) (PubMed).

Détails sur EPH Receptor B3

Antigène: EPH Receptor B3 (EPHB3)

Autre désignation: EphB3 (EPHB3 Produits)

Synonymes: anticorps tck, anticorps MGC83457, anticorps EPHB3, anticorps ETK2, anticorps HEK2, anticorps TYRO6, anticorps AW456895, anticorps Cek10, anticorps Etk2, anticorps MDK5, anticorps Sek4, anticorps Tyro6, anticorps CEK10, anticorps EK10, anticorps ek3, anticorps ephb3, anticorps fc62d03, anticorps rtk3, anticorps wu:fc62d03, anticorps zek3, anticorps EPH receptor B3, anticorps EPH receptor B3 L homeolog, anticorps Eph receptor B3, anticorps eph receptor B3a, anticorps Eph receptor tyrosine kinase, anticorps EPHB3, anticorps ephb3.L, anticorps ephb3, anticorps Ephb3, anticorps ephb3a

Sujet: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB3, a member of the Tyr family of protein kinases, is a receptor for members of the ephrin-B family, it binds to both ephrin-B1 and -B2. Expression of this Type I membrane protein is ubiquitous. The protein contains putative domains for 2 fibronectin type III and 1 sterile alpha motif (SAM).

Poids moléculaire: 110330

ID gène: 2049

NCBI Accession: NP_004434

UniProt: P54753

Pathways: Signalisation RTK