Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This FUCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human FUCA2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Waidely, Al-Youbi, Bashammakh, El-Shahawi, Leblanc: "Study of the Alpha-l-Fucosidase Langmuir Monolayer at the Air-Water Interface." dans: The journal of physical chemistry. B, Vol. 120, Issue 50, pp. 12843-12849, (2018) (PubMed).
Waidely, Al-Youbi, Bashammakh, El-Shahawi, Leblanc: "Alpha-l-Fucosidase Immunoassay for Early Detection of Hepatocellular Carcinoma." dans: Analytical chemistry, Vol. 89, Issue 17, pp. 9459-9466, (2017) (PubMed).
Alpha-L-fucosidase catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.