MUSK anticorps
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- Antigène Voir toutes MUSK Anticorps
- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MUSK est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogène
- This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
- Clone
- RB14743
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MUSK Anticorps primaire
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- Indications d'application
- IF: 1:10~50. WB: 1:1000. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
- Autre désignation
- MUSK (MUSK Produits)
- Sujet
- MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
- Poids moléculaire
- 97056
- ID gène
- 4593
- NCBI Accession
- NP_001159752, NP_001159753, NP_005583
- UniProt
- O15146
- Pathways
- Signalisation RTK, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
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