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RYK anticorps (AA 160-190)

RYK Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal RB1491 unconjugated
N° du produit ABIN392050
  • Antigène Voir toutes RYK Anticorps
    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
    Épitope
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-190
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 60
    • 13
    • 3
    • 1
    Lapin
    Clonalité
    • 66
    • 11
    Polyclonal
    Conjugué
    • 32
    • 8
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RYK est non-conjugé
    Application
    • 65
    • 49
    • 32
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This RYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from human RYK.
    Clone
    RB1491
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze-thaw cycles.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Date de péremption
    6 months
  • Povinelli, Nemeth: "Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor." dans: Stem cells (Dayton, Ohio), Vol. 32, Issue 1, pp. 105-15, (2014) (PubMed).

    González, Fernández-Martos, Arenas, Rodríguez: "The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury." dans: Journal of neurotrauma, Vol. 30, Issue 10, pp. 806-17, (2013) (PubMed).

    Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." dans: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

    Miyashita, Koda, Kitajo, Yamazaki, Takahashi, Kikuchi, Yamashita: "Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury." dans: Journal of neurotrauma, Vol. 26, Issue 7, pp. 955-64, (2009) (PubMed).

  • Antigène
    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
    Autre désignation
    RYK (RYK Produits)
    Synonymes
    anticorps RYK, anticorps jtk5, anticorps ryk1, anticorps jtk5a, anticorps d3s3195, anticorps wu:fb37b12, anticorps wu:fi05b06, anticorps zgc:158381, anticorps MGC114645, anticorps D3S3195, anticorps JTK5, anticorps JTK5A, anticorps RYK1, anticorps AW536699, anticorps ERK-3, anticorps Vik, anticorps receptor-like tyrosine kinase, anticorps receptor-like tyrosine kinase S homeolog, anticorps tyrosine-protein kinase RYK, anticorps RYK, anticorps ryk, anticorps ryk.S, anticorps LOC100541106, anticorps Ryk
    Sujet
    RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
    Poids moléculaire
    67815
    ID gène
    6259
    NCBI Accession
    NP_001005861, NP_002949
    UniProt
    P34925
    Pathways
    Signalisation RTK, Signalisation WNT, Regulation of Cell Size
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