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TRIB1 anticorps (C-Term)

TRIB1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB9762 unconjugated
N° du produit ABIN392118
  • Antigène Voir toutes TRIB1 Anticorps
    TRIB1 (Tribbles Homolog 1 (TRIB1))
    Épitope
    • 15
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 341-370, C-Term
    Reactivité
    • 51
    • 15
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 4
    • 3
    Lapin
    Clonalité
    • 49
    • 3
    Polyclonal
    Conjugué
    • 22
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRIB1 est non-conjugé
    Application
    • 38
    • 22
    • 13
    • 13
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1.
    Clone
    RB9762
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TRIB1 Anticorps primaire
  • Indications d'application
    WB: 1:2000. WB: 1:2000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Makishima, Boonvisut, Ishizuka, Watanabe, Nakayama, Iwamoto: "Sin3A-associated protein, 18 kDa, a novel binding partner of TRIB1, regulates MTTP expression." dans: Journal of lipid research, Vol. 56, Issue 6, pp. 1145-52, (2015) (PubMed).

    Ishizuka, Nakayama, Ogawa, Makishima, Boonvisut, Hirao, Iwasaki, Yada, Yanagisawa, Miyashita, Takahashi, Iwamoto: "TRIB1 downregulates hepatic lipogenesis and glycogenesis via multiple molecular interactions." dans: Journal of molecular endocrinology, Vol. 52, Issue 2, pp. 145-58, (2014) (PubMed).

    Dugast, Kiss-Toth, Docherty, Danger, Chesneau, Pichard, Judor, Pettré, Conchon, Soulillou, Brouard, Ashton-Chess: "Identification of tribbles-1 as a novel binding partner of Foxp3 in regulatory T cells." dans: The Journal of biological chemistry, Vol. 288, Issue 14, pp. 10051-60, (2013) (PubMed).

  • Antigène
    TRIB1 (Tribbles Homolog 1 (TRIB1))
    Autre désignation
    TRIB1 (TRIB1 Produits)
    Sujet
    TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.
    Poids moléculaire
    41009
    ID gène
    10221
    NCBI Accession
    NP_079471
    UniProt
    Q96RU8
    Pathways
    Smooth Muscle Cell Migration
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