ANTXR1 anticorps (AA 358-386)
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- Antigène Voir toutes ANTXR1 Anticorps
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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Épitope
- AA 358-386
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ANTXR1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This ANTXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from human ANTXR1.
- Clone
- RB15324
- Isotype
- Ig Fraction
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- Indications d'application
- WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- Autre désignation
- ANTXR1 (ANTXR1 Produits)
- Synonymes
- anticorps ANTXR1, anticorps ATR, anticorps TEM8, anticorps 2310008J16Rik, anticorps 2810405N18Rik, anticorps Antrx1, anticorps Tem8, anticorps anthrax toxin receptor 1, anticorps ANTXR1, anticorps Antxr1
- Sujet
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
- Poids moléculaire
- 62789
- ID gène
- 84168
- NCBI Accession
- NP_060623, NP_115584, NP_444262
- UniProt
- Q9H6X2
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