PTK7 anticorps (N-Term)

N° du produit ABIN392230

Détail du produit anti-PTK7 anticorps

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Épitope: AA 21-52, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTK7 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCK4 (PTK7) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human CCK4 (PTK7).

Clone: RB01501

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000-1:2000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PTK7 (ABIN392230)

Wang, Li, Yin, Wang, Wang, Wei, Guo, Ma, Shi, Zhou, Wang: "PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7881-9, (2014) (PubMed).

Détails sur PTK7

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Autre désignation: CCK4 (PTK7) (PTK7 Produits)

Synonymes: anticorps PTK7, anticorps CCK-4, anticorps CCK4, anticorps Srf, anticorps 8430404F20Rik, anticorps chz, anticorps mPTK7/CCK4, anticorps KLG, anticorps protein tyrosine kinase 7 (inactive), anticorps protein tyrosine kinase 7, anticorps PTK7 protein tyrosine kinase 7, anticorps PTK7, anticorps Ptk7

Sujet: CCK4 may function as a cell adhesion molecule. Although it belongs to the insuline receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.

Poids moléculaire: 118392

ID gène: 5754

NCBI Accession: NP_001257327, NP_002812, NP_690619, NP_690620, NP_690621

UniProt: Q13308

Pathways: Signalisation RTK, Tube Formation