PRKG1 anticorps (C-Term)
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- Antigène Voir toutes PRKG1 Anticorps
- PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
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Épitope
- AA 629-660, C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRKG1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- B
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This cGKI (cGKI beta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-660 amino acids from the C-terminal region of human cGKI beta.
- Clone
- RB1046
- Isotype
- Ig Fraction
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- Indications d'application
- WB: 1:1000. WB: 1:1000. IHC-P: 1:100. IHC-P: 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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-
A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension." dans: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16557-66, (2013) (PubMed).
: "
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A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension." dans: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16557-66, (2013) (PubMed).
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- Antigène
- PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
- Autre désignation
- cGKI (cGKI beta) (PRKG1 Produits)
- Synonymes
- anticorps prkg1, anticorps zgc:63955, anticorps Pkgi, anticorps cGk1, anticorps 1, anticorps PKG, anticorps PRKG1B, anticorps PRKGR1B, anticorps cGK, anticorps cGK 1, anticorps cGK1, anticorps cGKI, anticorps cGKI-BETA, anticorps cGKI-alpha, anticorps CGKI, anticorps cGKI-beta, anticorps AW125416, anticorps Gm19690, anticorps Prkg1b, anticorps Prkgr1b, anticorps Prkg1beta, anticorps protein kinase, cGMP-dependent, type Ia, anticorps protein kinase, cGMP-dependent, type I, anticorps protein kinase, cGMP-dependent, type 1, anticorps prkg1a, anticorps PRKG1, anticorps prkg1, anticorps Prkg1
- Sujet
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
- Poids moléculaire
- 76364
- ID gène
- 5592
- NCBI Accession
- NP_001091982, NP_006249
- UniProt
- Q13976
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