PIK3R2 anticorps (AA 442-471)

N° du produit ABIN392582

Détail du produit anti-PIK3R2 anticorps

Antigène: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Épitope: AA 442-471

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3R2 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PIK3R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-471 amino acids from human PIK3R2.

Clone: RB13727

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur PIK3R2

Antigène: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Autre désignation: PIK3R2 (PI3K p85b Produits)

Synonymes: anticorps MPPH, anticorps P85B, anticorps p85, anticorps p85-BETA, anticorps pik3r2, anticorps MGC80449, anticorps p85beta, anticorps phosphoinositide-3-kinase regulatory subunit 2, anticorps phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta), anticorps phosphoinositide-3-kinase, regulatory subunit 2 (beta), anticorps PIK3R2, anticorps pik3r2, anticorps Pik3r2

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.

Poids moléculaire: 81545

ID gène: 5296

NCBI Accession: NP_005018

UniProt: O00459

Pathways: VEGF Signaling, BCR Signaling