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PLK3 anticorps (C-Term)

PLK3 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB0875 unconjugated
N° du produit ABIN392602
  • Antigène Voir toutes PLK3 Anticorps
    PLK3 (Polo-Like Kinase 3 (PLK3))
    Épitope
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 615-646, C-Term
    Reactivité
    • 45
    • 23
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 41
    • 2
    • 2
    Lapin
    Clonalité
    • 45
    Polyclonal
    Conjugué
    • 23
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PLK3 est non-conjugé
    Application
    • 37
    • 29
    • 20
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This PLK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 615-646 amino acids from the C-terminal region of human PLK3.
    Clone
    RB0875
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PLK3 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Zhang, Shi, Paddon, Hampong, Dai, Pelech: "B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1." dans: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 35726-34, (2004) (PubMed).

  • Antigène
    PLK3 (Polo-Like Kinase 3 (PLK3))
    Autre désignation
    PLK3 (PLK3 Produits)
    Synonymes
    anticorps cnk, anticorps wu:fi35f10, anticorps fnk, anticorps prk, anticorps plx3, anticorps MGC89507, anticorps PLK2/3, anticorps NV15469, anticorps Plx3, anticorps CNK, anticorps FNK, anticorps PRK, anticorps Cnk, anticorps Fnk, anticorps polo-like kinase 3 (Drosophila), anticorps polo like kinase 3, anticorps polo-like kinase 3, anticorps polo-like kinase 3 S homeolog, anticorps polo-like kinase 3 L homeolog, anticorps Serine/threonine-protein kinase plk-3, anticorps plk3, anticorps PLK3, anticorps LOC100118436, anticorps plk3.S, anticorps plk3.L, anticorps Plk3, anticorps plk-3
    Sujet
    CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M phase functions during the cell cycle. It may also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein. This membrane-associated protein binds to the calcium/integrin-binding protein (CIB). This interaction probably occurs via the POLO-box domain. Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. This protein exhibits a short half-live. In cells of hematopoietic origin, CNK is strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor. Cytokine and cellular adhesion trigger CNK induction. CNK is thought to be phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis The protein contains 2 POLO box domains.
    Poids moléculaire
    71629
    ID gène
    1263
    NCBI Accession
    NP_004064
    UniProt
    Q9H4B4
    Pathways
    Regulation of long-term Neuronal Synaptic Plasticity
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